3,5-Difluorophenol, identified by CAS 2713-34-0, is a fluorinated phenolic building block used primarily in research, pharmaceutical intermediate development, and specialty organic synthesis. Its molecular formula is C6H4F2O, and its molecular weight is 130.09 g/mol. I recommend treating it as a project-specific intermediate: the correct grade, assay, impurity profile, packaging, and documentation should be confirmed against the buyer’s reaction and regulatory requirements before purchase.
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At Maison Chemical, I help B2B buyers evaluate 3,5-Difluorophenol not only by price, but also by identity confirmation, batch consistency, supply continuity, and documentation. This guide explains what to check, how to compare suppliers, and what information to include in a technical inquiry.
This guide is intended for procurement teams, process chemists, pharmaceutical intermediate manufacturers, contract research organizations, and distributors sourcing 3,5-Difluorophenol CAS 2713-34-0. It is also useful for buyers who are moving from milligram-scale laboratory work toward gram- or kilogram-scale development. I focus on practical B2B decisions rather than presenting the material as a finished pharmaceutical ingredient.
The compound may be relevant when a synthesis requires both a phenolic hydroxyl group and fluorine substitution on an aromatic ring. However, suitability depends on the downstream reaction, reaction conditions, impurity tolerance, and the quality level required by the customer’s internal specification.
| Item | Information | Buyer Relevance |
|---|---|---|
| Product name | 3,5-Difluorophenol | Use the exact name to avoid confusion with other difluorophenol isomers. |
| CAS number | 2713-34-0 | Confirm identity across quotations, documents, and customs records. |
| Molecular formula | C6H4F2O | Useful for reaction calculations and analytical review. |
| Molecular weight | 130.09 g/mol | Required for molar equivalent calculations and material planning. |
3,5-Difluorophenol contains an aromatic phenol structure with fluorine atoms at the 3 and 5 positions relative to the hydroxyl group. This substitution pattern can influence electronic properties and reaction behavior compared with unsubstituted phenol or other positional isomers. I advise chemists to confirm the intended substitution pattern before approving a purchase, because positional isomers can have different reactivity and analytical profiles.
In B2B sourcing, “grade” should describe a documented quality requirement rather than a vague marketing label. A buyer may need a research grade for route scouting, a higher-purity material for process development, or a lot-controlled intermediate for manufacturing support. These categories should be defined by assay, related substances, water, residual solvents, appearance, and analytical methods where relevant.
Packaging can also be tailored to the project stage. Small quantities may be appropriate for laboratory evaluation, while larger quantities require stronger controls for container compatibility, labeling, traceability, and transportation. I do not recommend assuming that a laboratory pack and a production-support pack have identical documentation or commercial terms.
A typical technical review begins with identity and assay, but it should not end there. I recommend requesting a current certificate of analysis, analytical method information where available, batch or lot identification, and a safety data sheet. If the compound will enter a regulated development program, the buyer should also define documentation expectations before the quotation stage.
| Specification Area | What to Confirm | Why It Matters |
|---|---|---|
| Identity | CAS number, name, formula, and analytical confirmation | Reduces the risk of ordering the wrong isomer or material. |
| Assay | Buyer-defined target, commonly expressed as a percentage | Supports stoichiometric accuracy and impurity control. |
| Related substances | Known or unknown impurities and reporting threshold | Important for downstream purification and regulatory review. |
| Physical description | Appearance and condition as stated on the supplier specification | Provides a basic incoming quality check. |
| Packaging | Container type, net weight, labeling, and sealing | Supports safe handling and inventory control. |
| Documents | COA, SDS, batch information, and shipping documents | Helps quality, EHS, logistics, and purchasing teams work from the same data. |
An assay value such as 98% or 99% should never be presented as a guaranteed product result unless it appears in the agreed specification and is supported by the relevant batch documentation. For example, a buyer may request a minimum assay of 98%, but the final acceptance criterion should be confirmed between the technical and quality teams. At Maison Chemical, I prefer to clarify this point before order confirmation rather than leave the requirement implicit.
3,5-Difluorophenol can serve as an aromatic building block in the preparation of more complex fluorinated intermediates. Its use may involve transformations of the phenolic group or further functionalization of the aromatic ring, depending on the synthetic route. The actual application must be assessed by the customer’s chemist because route compatibility cannot be established from the product name alone.
Fluorinated phenols are often evaluated when researchers want to adjust the electronic or lipophilic characteristics of an aromatic fragment. This does not mean that every fluorinated phenol is interchangeable. I recommend comparing the 3,5-substitution pattern with alternative isomers during route selection, especially when selectivity, purification, or scale-up behavior is important.
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At early development stages, buyers may prioritize availability, analytical clarity, and flexible pack sizes. During process development, they usually need tighter control of lot-to-lot variation, impurity patterns, and replenishment timing. A supplier that can discuss both technical and commercial requirements is more useful than one that provides only a nominal price.
Start with the exact CAS number, required quantity, target assay, acceptable impurity limits, packaging preference, delivery location, and intended use. If the material is for a regulated or customer-facing project, list the required documents at the same time. This prevents a quotation from being technically incomplete.
Review whether the supplier can provide a representative COA, SDS, product specification, and batch traceability information. Check whether the analytical method is clear enough for your incoming quality process. I also recommend asking how deviations, retesting, and nonconforming material are handled.
Ask whether the quoted material is available from existing inventory or requires production planning. For planning purposes, some projects may use an indicative lead-time window of 5–15 business days, but this is not a universal commitment and must be confirmed for the exact quantity, destination, and documentation package. Transportation classification, packaging, export paperwork, and local import requirements can all affect the final schedule.
Price should be evaluated together with minimum order quantity, packaging loss, payment terms, shipping cost, and the risk of requalification. A lower unit price may not be advantageous if it creates excessive inventory or lacks the documents required by your quality system. I encourage buyers to compare total sourcing cost rather than quotation price alone.
One common mistake is confusing 3,5-Difluorophenol with another difluorophenol isomer. Another is accepting an assay statement without confirming the test method, batch number, or impurity limits. Buyers may also overlook whether the packaging and transport documents are suitable for their destination.
A further risk is requesting a large volume before the material has passed a route-specific evaluation. Where practical, I suggest starting with a qualification quantity, reviewing analytical and reaction performance, and then agreeing on a larger supply plan. This staged approach can reduce technical and commercial exposure without assuming that small-scale performance guarantees production results.
Maison Chemical supports B2B inquiries for 3,5-Difluorophenol CAS 2713-34-0 by discussing product identity, quantity, target quality, packaging, documentation, and delivery requirements. I can help organize the information needed for a technical quotation and identify which specifications must be confirmed before order placement. Where a project has special quality or logistics requirements, those details should be included in the initial inquiry.
Our role as a manufacturer, supplier, and export-oriented chemical partner is to provide a clear communication path between purchasing, technical, quality, and logistics teams. Availability, minimum order quantity, lead time, and final commercial terms depend on the specific order and destination. For that reason, I recommend requesting a current quotation rather than relying on general market assumptions.
3,5-Difluorophenol CAS 2713-34-0 can be a useful fluorinated aromatic building block for pharmaceutical intermediate and specialty synthesis projects, but the right purchasing decision depends on more than the chemical name. I recommend confirming the exact isomer, defining a written specification, reviewing batch documentation, and evaluating the supplier’s ability to support both immediate needs and future replenishment.
To begin an inquiry with Maison Chemical, please provide the required quantity, target assay or specification, packaging preference, destination country, intended application category, and requested delivery schedule. I can then help assess the appropriate supply option and clarify which quality and logistics details should be confirmed before purchase.
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